Contribution records linked to evidence

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A paper lists John, Mary, and Eve together. Benchpro shows that John designed the CRISPR screen, Mary ran single-cell RNA sequencing, and Eve built the analysis pipeline.

Each contribution links to its Methods or Supplement source and records confirmation by three co-authors.

Cell SystemsResearch article · 2025

Mapping regulators of stress resilience with pooled CRISPR screening

Methods excerpt · pooled screen + scRNA-seq

Abstract

We combined pooled perturbation screening with single-cell transcriptomics to resolve regulators of cellular stress response.

Methods

A genome-scale guide library was introduced across three biological replicates. Cell states were profiled by scRNA-seq and analysed in a reproducible pipeline.

John

Experimental design

Designed the CRISPR screen

Source Methods §2.1 Confirmed by 3 co-authors

Mary

Data generation

Ran single-cell RNA sequencing

Source Methods §3.4 Confirmed by 3 co-authors

Eve

Software & analysis

Built the analysis pipeline

Source Supplement S4 Confirmed by 3 co-authors
Linked source: Pooled CRISPR study, 2025

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  1. 01 · Record

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    Example imported publication

    Mapping regulators of stress resilience with pooled CRISPR screening

    Cell Systems · 2025 · John, Mary, Eve, et al.

    Contribution record

    John · Designed the CRISPR screen

    Linked source: Methods §2.1

    Awaiting co-author confirmation

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  2. 02 · Review

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    Contribution record

    John · Designed the CRISPR screen

    Linked source: Methods §2.1

    Co-author review

    Three responses received

    • A. BrownConfirmed
    • L. ChenConfirmed
    • R. KumarConfirmed

    Confirmed by 3 co-authors

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  3. 03 · Share

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    Confirmed contribution

    John · Designed the CRISPR screen

    Linked source: Methods §2.1

    Confirmed by 3 co-authors

    Example opportunity

    Pooled screening study design

    Matched evidence: CRISPR screen design

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